CellChek SL

The global golden standard in endothelial analytics

CellChek Clinical Benefits

Cataract Surgery and Premium IOLs

Low endothelial cell counts and pre-existing dystrophies can markedly reduce the potential for positive surgical outcomes from an otherwise uneventful cataract surgery. Surgeons are finding these data points critical when recommending premium IOLs: verify and document pre-operatively that the cornea is not suspect to more likely post-op complications difficult to explain with the investment in premium IOLs.

Refractive Surgery

There are various reports in the literature of refractive surgery complications with corneas that have pre-existing dystrophies. It is incumbent on refractive surgeons and referring Optometrists to carefully assess the corneal health prior to performing or recommending an elective corneal surgery to enhance the potential for positive surgical outcomes.

General Corneal Health Assessment

Konan specular microscopy is an invaluable tool to screen for corneal diseases as such as Fuchs’ Dystrophy, keratoconus, other corneal dystrophies, and trauma. You won’t believe what you’ve been missing.

Contact Lenses

In the never ending battle to minimize the oxygen barrier from contact lens materials and lens hygiene, specular microscopy provides a highly detailed view of the integrity and distress of the cornea from the endothelium. As the “canary in the coal mine”, the endothelium can be an invaluable indicator of corneal distress.

Konan Cellcheck
Konan Cellcheck
Konan Cellcheck
Konan Cellcheck
Konan Cellcheck

It is not a coincidence...

… that virtually every manufacturer of pharmaceutical agents and implantable devices that are required by the FDA to collect endothelial density as a primary safety endpoint, have had their clinical research teams, completely independently, assess the specular microscopes available on the market and have chosen Konan. Repeatedly.


Cutting edge technology in a compact, portable device with extremely low operating costs

EvokeDx is the next generation icVEP + VEP + ERG device developed by Konan Medical and leading scientists in visual electrophysiology.  Its compact, all-in-one form factor features numerous market-leading technologies including:  intuitive touch-screen user interface Organic LED stimulus display, infrared gaze and attention monitoring dual-channel amplifier, and powerful Fourier (Frequency domain) analytics with intuitive reporting. EvokeDx is a fresh approach to visual electrophysiology.

EvokeDx Clinical Benefits

Visual Evoked Potentials (VEP) provide objective, quantitative information about the functional integrity of discrete visual pathways in a non-invasive manner. This is new information that is complementary to the structural analysis obtained from technologies such as OCT and Fundus photography, and augments subjective information from standard visual acuity and perimetry. Electroretinograms (ERG) reflect the integrity of the optics, photoreceptors, bipolar cells and retinal ganglion cells. Clinically, ERGs may be useful when patients have abnormal VEPs to differentiate between retinal dysfunction occurring in the optic nerve, optic radiations and occipital cortex.

Operator Aspect

The Operator side of EvokeDx features an intuitive, touch-screen enabled user experience graphically guiding the operator easily through the test sequence:

  • patient add | select
  • test select
  • patient alignment
  • testing
  • results / analytics
  • preferences / settings

Analytics instantly displays test results and Fourier analytics. One-touch help screens provide context-sensitive explanations of all analytic components for all tests. A robust comparison feature allows instant comparisons. For example:

  • compare right and left eyes on same day
  • compare same eye from a prior exam to assess progression
  • compare how a bright response compares to dark response, same pattern
  • compare how a small check response compares to large check response
  • compare how one patient compares to another patient of known characteristics
Operator side of EvokeDx

Patient Aspect

The patient side of EvokeDx features a high specification OLED stimulus display, patient gaze / attention tracking, and easy plug-in for electrodes to internal dual-channel amplifier. Say goodbye to asking the patient to hold a single-channel amplifier!


The most significant advancement in pupil testing in over a century

Historical Methods: The “Swinging Flashlight Test”

With origins stemming from the 19th century, this manual and subjective method of detecting an RAPD is commonly known to be difficult to perform well, under the best of circumstances. Although known to be an important physical sign, many well-intentioned doctors report little incidence – not because the sign is not present, but because it is difficult or impossible to detect and it is rarely quantified.

A Perfect Storm

Confounding issues such as minimum contrast (dark iris + black pupil + dark room), anisocoria, misshapen pupils and the lack of standardized light intensity conspire to make the swinging flashlight test even more challenging.

RAPDX with preview

Enter RAPDx

RAPDx utilizes a high-definition, machine-vision system under controlled infrared conditions to present monocular visual stimuli while recording binocular pupil responses. Unlike human observers that only see one eye response at a time, RAPDx simultaneous images both direct and consensual light responses. The power of the system is to collect a series of responses and average them into a consolidated response curve. Pupil testing is notoriously non-standardized, variable, and noisy. Response averaging significantly helps filter the noise inherent in the biological responses.

Easy, objective, quantitative, delegated, detailed … perhaps better than the finest human observer. RAPDx may be the most significant advancement in pupil testing in decades.


The most significant advancement in pupil testing in over a century

Tritan deficiencies are rarely genetic, yet as high as 15% of the general population may have a tritan deficiency. This is an important but often overlooked sign that may be caused by retinal, optic nerve, or neurological disorders, in addition to trauma, cataracts, and hundreds of common drugs and substances.

Testing for acquired color vision deficiencies is underutilized. Traditional tests like the D15 have low sensitivity, while the more sensitive D100 simply takes too long to be practical. Other computerized color vision tests are expensive, costing thousands more than ColorDx.

konan colordx

ColorDx Applications

Military-grade, professional tests using the Waggoner six-confusion color strategy: “Extended” for qualitative and quantitative assessment of both genetic (Protan – Deutan) and acquired (Tritan) color vision deficiencies. “Pediatric” for genetic deficiencies featuring the world’s most popular Color Vision Testing Made Easy strategy tailored to young children.

ColorDx – professional color vision diagnostic applications


Pediatric Color Vision Testing

Approximately 8% of males and 0.5% of females are born with color vision deficiencies, therefore children, especially males, should have their color vision tested before they start school, ideally in pre-school. Awareness of color vision deficiencies in children is critical for learning and socializing.

The Pediatric test (Dr. Waggoner’s “CVTME” Color Vision Testing Made Easy) is the gold standard for child / illiterate friendly color vision tests and is now available electronically on all ColorDx platforms.

  • Quick to administer
  • Takes only about 1 minute
  • Easy to understand, easy to take
  • Clinically relevant
Pediatric Color Vision Testing
konan ColorDx

Vocational and Acquired Color Vision Deficiency Testing

Many occupations and professions require normal color vision to either perform the job or to maintain public safety. Examples include military and civilian pilots (and navigators), air traffic controllers, nurses, lab technicians, school bus drivers, some law enforcement personnel, electricians, electronic technicians, and railroad conductors.

This is a comprehensive test validated by thr Naval Aerospace Medical Institute for assessment of color vision deficiencies by type (Protan, Deutan, Tritan) and severity (mild, moderate, severe), and generates a self-scored report. A focused test specific to Tritan deficiencies is also available when genetic deficiencies have been previously screened for a substance / drug / disease that may produce an acquired deficiency is suspected .

Pediatric Color Vision Testing

Want to offer cutting-edge treatment to your patients?