Clearly Focused On Improving Vision
BioDOptix® is a dehydrated, extracellular membrane allograft derived from human amniotic tissue that is intended for homologous use as a scaffold for ocular tissue repair.
• Dehydrated using our proprietary DryFlex® process that preserves the inherent extracellular matrix, growth factors, and cytokines of the amniotic tissue
• Easy to apply and conforms well to the anterior ocular surface
• Placement generally does not require sutures or glue
• Circular or rectangular sizes for appropriate fit.
• Dehydrated product allows for easy trim-to-size fitting
• Room temperature storage with 5 year shelf life
• Convenient for use in inpatient, outpatient or clinic settings
• Amniotic tissues have been described as immune-privileged because they rarely evoke an immune response in the human body1
• Tissue recovered from live, healthy donors during cesarean childbirth
• Donor selection, tissue recovery and processing protocols and procedures meet or exceed all applicable industry standards to ensure patient safety
• Amniotic extracellular matrix composition of collagen, elastin, fibronectin and proteoglycans provides a natural scaffold to facilitate cellular adhesion while assisting cellular migration and proliferation.2
• Amniotic tissue has been shown to help reduce inflammation and pain, scar tissue formation, and the risk of infection.2, 3
Common Clinical Applications of Amniotic Tissues
- Ocular Surface Disorders
- Corneal Epithelial Defects
- Corneal Ulcer
- Adjunctive Therapy for PK Cornea Transplant
- Band Keratopathy
- Bullous Keratopathy
- OX-010152 – 1.5 x 2.0cm2
- OX-010203 – 2.0 x 3.0cm2
- OX-010009 – 9.0mm disc
- OX-010012 – 12.0mm disc
- OX-010015 – 15.0mm disc
1. Kubo, et al. Immunogenicity of Human Amniotic Membrane in Experimental Xenotransplantation. Investigative Ophthalmology & Visual Science, June 2001, Vol. 42, No. 7.
2. Niknejad, H, et al. Properties of amniotic membrane for potential use in Tissue Engineering. European Cells and Materials 2008; Vol 15: 88-99.
3. Gruss, J, et al. Human amniotic membrane: a versatile wound dressing. CMA Journal 1978; Vol 118: 1237-1246.